BACKGROUND: Effective and measurable participant recruitment methods are urgently needed for clinical studies in Alzheimer’s disease. OBJECTIVES: To develop methods for measuring recruitment tactics and evaluating effectiveness. METHODS: Recruitment tactics for the Alzheimer’s Disease Neuroimaging Initiative (ADNI3) were measured using… Continue Reading →
The most common dementia worldwide, Alzheimer’s disease is often diagnosed via biomarkers in cerebrospinal fluid, including reduced levels of Aβ1–42, and increases in total tau and phosphorylated tau-181. Here we describe results of a Phase 2a study of a promising… Continue Reading →
Background: The use of magnetic resonance imaging (MRI) derived functional cross-sectional area (FCSA) and intramuscular adipose tissue (IMAT) to define skeletal muscle quality is of fundamental importance in order to understand aging and inactivity-related loss of muscle mass. Objectives: This… Continue Reading →
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